Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development

Creating complex multicellular kidney organoids from pluripotent stem cells shows great promise. Further improvements in differentiation outcomes, patterning, and maturation of specific cell types are, however, intrinsically limited by standard tissue culture approaches. We describe a novel full fac...

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Publicat a:Sci Adv
Autors principals: Glass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H., Cooper-White, Justin J.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949035/
https://ncbi.nlm.nih.gov/pubmed/31934619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw2746
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