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YAP1 oncogene is a context-specific driver for pancreatic ductal adenocarcinoma

Transcriptomic profiling classifies pancreatic ductal adenocarcinoma (PDAC) into several molecular subtypes with distinctive histological and clinical characteristics. However, little is known about the molecular mechanisms that define each subtype and their correlation with clinical outcome. Mutant...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Tu, Bo, Yao, Jun, Ferri-Borgogno, Sammy, Zhao, Jun, Chen, Shujuan, Wang, Qiuyun, Yan, Liang, Zhou, Xin, Zhu, Cihui, Bang, Seungmin, Chang, Qing, Bristow, Christopher A., Kang, Ya’an, Zheng, Hongwu, Wang, Huamin, Fleming, Jason B., Kim, Michael, Heffernan, Timothy P., Draetta, Giulio F., Pan, Duojia, Maitra, Anirban, Yao, Wantong, Gupta, Sonal, Ying, Haoqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948828/
https://ncbi.nlm.nih.gov/pubmed/31557131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130811
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