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Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes

Mesenchymal stromal/stem cell (MSC) therapy has shown promise in experimental models of idiopathic pulmonary fibrosis (IPF). The aim of this study was to test the therapeutic effects of extracellular vesicles produced by human BM MSCs (MEx) in a bleomycin-induced pulmonary fibrosis model and investi...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Mansouri, Nahal, Willis, Gareth R., Fernandez-Gonzalez, Angeles, Reis, Monica, Nassiri, Sina, Mitsialis, S. Alex, Kourembanas, Stella
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948760/
https://ncbi.nlm.nih.gov/pubmed/31581150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128060
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