N-Acyl Homoserine Lactone Analog Modulators of the Pseudomonas aeruginosa Rhll Quorum Sensing Signal Synthase

Virulence in the Gram-negative pathogen Pseudomonas aeruginosa relies in part on the efficient functioning of two LuxI/R dependent quorum sensing (QS) cascades, namely, the LasI/R and RhlI/R systems that generate and respond to N-(3-oxo)-dodecanoyl-l-homoserine lactone and N-butyryl-l-homoserine lac...

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書誌詳細
出版年:ACS Chem Biol
主要な著者: Shin, Daniel, Gorgulla, Christoph, Boursier, Michelle E., Rexrode, Neilson, Brown, Eric C., Arthanari, Haribabu, Blackwell, Helen E., Nagarajan, Rajesh
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6948153/
https://ncbi.nlm.nih.gov/pubmed/31545595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00671
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