Neurovascular effects of umbilical cord blood-derived stem cells in growth-restricted newborn lambs: UCBCs for perinatal brain injury

BACKGROUND: Neonatal ventilation exacerbates brain injury in lambs with fetal growth restriction (FGR), characterized by neuroinflammation and reduced blood-brain barrier integrity, which is normally maintained by the neurovascular unit. We examined whether umbilical cord blood stem cell (UCBC) trea...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Malhotra, Atul, Castillo-Melendez, Margie, Allison, Beth J., Sutherland, Amy E., Nitsos, Ilias, Pham, Yen, McDonald, Courtney A., Fahey, Michael C., Polglase, Graeme R., Jenkin, Graham, Miller, Suzanne L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947982/
https://ncbi.nlm.nih.gov/pubmed/31915068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1526-0
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