Curcumin analog A13 alleviates oxidative stress by activating Nrf2/ARE pathway and ameliorates fibrosis in the myocardium of high-fat-diet and streptozotocin-induced diabetic rats

BACKGROUND: Diabetes mellitus is an important risk factor for cardiomyopathy. Increasing oxidative stress may be one of the main factors of diabetic cardiomyopathy. A13, a newly synthesized curcumin analog, was proved to be superior to curcumin in biological activity. However, little know about how...

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Detalhes bibliográficos
Publicado no:Diabetol Metab Syndr
Main Authors: Xiang, Lanting, Zhang, Qiongying, Chi, Chen, Wu, Gu, Lin, Zhongmin, Li, Jianmin, Gu, Qianru, Chen, Guorong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947902/
https://ncbi.nlm.nih.gov/pubmed/31921358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13098-019-0485-z
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