Leptin Modulates the Expression of miRNAs-Targeting POMC mRNA by the JAK2-STAT3 and PI3K-Akt Pathways

The central control of energy balance involves a strongly regulated neuronal network within the hypothalamus and the brainstem. In these structures, pro-opiomelanocortin (POMC) neurons are known to decrease food intake and to increase energy expenditure. Thus, leptin, a peripheral signal that relays...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Derghal, Adel, Astier, Julien, Sicard, Flavie, Couturier, Charlène, Landrier, Jean-François, Mounien, Lourdes
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947463/
https://ncbi.nlm.nih.gov/pubmed/31847355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8122213
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