HPMC- and PLGA-Based Nanoparticles for the Mucoadhesive Delivery of Sitagliptin: Optimization and In Vivo Evaluation in Rats

Mucoadhesive nanoparticles represent a potential drug delivery strategy to enhance the therapeutic efficacy in oral therapy. This study assessed the prospective of developing HPMC- and PLGA-based nanoparticles using a nanospray drier as a mucoadhesive extended release drug delivery system for sitagl...

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發表在:Materials (Basel)
Main Authors: Nair, Anroop B., Sreeharsha, Nagaraja, Al-Dhubiab, Bandar E., Hiremath, Jagadeesh G., Shinu, Pottathil, Attimarad, Mahesh, Venugopala, Katharigatta N., Mutahar, Mohamed
格式: Artigo
語言:Inglês
出版: MDPI 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947415/
https://ncbi.nlm.nih.gov/pubmed/31861192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma12244239
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