Erastin Inhibits Septic Shock and Inflammatory Gene Expression via Suppression of the NF-κB Pathway

Sepsis is a life-threatening condition that is caused by an abnormal immune response to infection and can lead to tissue damage, organ failure, and death. Erastin is a small molecule capable of initiating ferroptotic cell death in cancer cells. However, the function of erastin in the inflammatory re...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Oh, Byung Moo, Lee, Seon-Jin, Park, Gyoung Lim, Hwang, Yo Sep, Lim, Jeewon, Park, Eun Sun, Lee, Kyung Ho, Kim, Bo Yeon, Kwon, Yong Tae, Cho, Hee Jun, Lee, Hee Gu
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947339/
https://ncbi.nlm.nih.gov/pubmed/31847346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8122210
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