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IGF-1R inhibitor PQ401 inhibits osteosarcoma cell proliferation, migration and colony formation

IGF-1R is expressed abnormally in osteosarcoma (OS) and could participate in its progression. In this study, we aimed to explore the effect of the IGF-1R inhibitor PQ401 as a treatment for OS. The relative expression of IGF-1R in OS patient tumors and the U2OS cell line were determined by qRT-PCR an...

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Détails bibliographiques
Publié dans:Int J Clin Exp Pathol
Auteurs principaux: Qi, Baochang, Zhang, Riping, Sun, Rujun, Guo, Mian, Zhang, Maomao, Wei, Guojun, Zhang, Lei, Yu, Shan, Huang, Hui
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947108/
https://ncbi.nlm.nih.gov/pubmed/31933976
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