Cardiac Differentiation of Adipose Tissue-Derived Stem Cells Is Driven by BMP4 and bFGF but Counteracted by 5-Azacytidine and Valproic Acid

OBJECTIVE: Bone morphogenetic protein 4 (BMP4) and basic fibroblast growth factor (bFGF) play important roles in embryonic heart development. Also, two epigenetic modifying molecules, 5ˊ-azacytidine (5ˊ-Aza) and valproic acid (VPA) induce cardiomyogenesis in the infarcted heart. In this study, we fi...

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Bibliografiske detaljer
Udgivet i:Cell J
Main Authors: Hasani, Sanaz, Javeri, Arash, Asadi, Asadollah, Taha, Masoumeh Fakhr
Format: Artigo
Sprog:Inglês
Udgivet: Royan Institute 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947007/
https://ncbi.nlm.nih.gov/pubmed/31863652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2020.6582
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