Effects of Sorafenib and Arsenic Trioxide on U937 and KG-1 Cell Lines: Apoptosis or Autophagy?

OBJECTIVE: Acute myeloid leukemia (AML) is a clonal disorder of hemopoietic progenitor cells. The Raf serine/threonine (Ser/Thr) protein kinase isoforms including B-Raf and RAF1, are the upstream in the MAPK cascade that play essential functions in regulating cellular proliferation and survival. Act...

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Vydáno v:Cell J
Hlavní autoři: Haghi, Atousa, Salami, Mahdieh, Mohammadi Kian, Mahnaz, Nikbakht, Mohsen, Mohammadi, Saeed, Chahardouli, Bahram, Rostami, Shaharbano, Malekzadeh, Kianoosh
Médium: Artigo
Jazyk:Inglês
Vydáno: Royan Institute 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947003/
https://ncbi.nlm.nih.gov/pubmed/31863650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2020.6728
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