Neurobiological divergence of the positive and negative schizophrenia subtypes identified upon a new factor-structure of psychopathology using non-negative factorization: An international machine-learning study

OBJECTIVE: Disentangling psychopathological heterogeneity in schizophrenia is challenging and previous results remain inconclusive. We employed advanced machine-learning to identify a stable and generalizable factorization of the “Positive and Negative Syndrome Scale (PANSS)”, and used it to identif...

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Publicado no:Biol Psychiatry
Main Authors: Chen, Ji, Patil, Kaustubh R., Weis, Susanne, Sim, Kang, Nickl-Jockschat, Thomas, Zhou, Juan, Aleman, André, Sommer, Iris E., Liemburg, Edith J., Hoffstaedter, Felix, Habel, Ute, Derntl, Birgit, Liu, Xiaojin, Kogler, Lydia, Regenbogen, Christina, Diwadkar, Vaibhav A., Stanley, Jeffrey A., Riedl, Valentin, Jardri, Renaud, Gruber, Oliver, Sotiras, Aristeidis, Davatzikos, Christos, Eickhoff, Simon B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946875/
https://ncbi.nlm.nih.gov/pubmed/31748126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.08.031
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