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Dynamic Characterization of Protein and Posttranslational Modification Levels in Mycobacterial Cholesterol Catabolism

Cholesterol of the host macrophage membrane is vital for mycobacterial infection, replication, and persistence. During chronic infection within host lung tissues, cholesterol facilitates the phagocytosis of mycobacteria into macrophages. Cholesterol degradation leads to increased flux of acetyl-coenz...

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Bibliografiske detaljer
Udgivet i:mSystems
Main Authors: Xu, Jun-Yu, Zhao, Lei, Xu, Ying, Li, Bolin, Zhai, Linhui, Tan, Minjia, Ye, Bang-Ce
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946793/
https://ncbi.nlm.nih.gov/pubmed/31911463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00424-19
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