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Bidirectional Optogenetically-Induced Plasticity of Evoked Responses in the Rat Medial Prefrontal Cortex Can Impair or Enhance Cognitive Set-Shifting

Chronic stress compromises cognition, including executive function mediated in the medial prefrontal cortex (mPFC). To investigate mechanisms underlying these processes, we use chronic unpredictable stress (CUS), which reduces activity in the mPFC and impairs cognitive set-shifting, a measure of cog...

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Pubblicato in:eNeuro
Autori principali: Bulin, Sarah E., Hohl, Kelly M., Paredes, Denisse, Silva, Jeri D., Morilak, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946542/
https://ncbi.nlm.nih.gov/pubmed/31852759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0363-19.2019
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