Acute ischemic stroke thrombi have an outer shell that impairs fibrinolysis

OBJECTIVES: Thrombi responsible for large vessel occlusion (LVO) in the setting of acute ischemic stroke (AIS) are characterized by a low recanalization rate after IV thrombolysis. To test whether AIS thrombi have inherent common features that limit their susceptibility to thrombolysis, we analyzed...

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Détails bibliographiques
Publié dans:Neurology
Auteurs principaux: Di Meglio, Lucas, Desilles, Jean-Philippe, Ollivier, Véronique, Nomenjanahary, Mialitiana Solo, Di Meglio, Sara, Deschildre, Catherine, Loyau, Stéphane, Olivot, Jean-Marc, Blanc, Raphaël, Piotin, Michel, Bouton, Marie-Christine, Michel, Jean-Baptiste, Jandrot-Perrus, Martine, Ho-Tin-Noé, Benoît, Mazighi, Mikael
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946479/
https://ncbi.nlm.nih.gov/pubmed/31541014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008395
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