Characterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII

TRAnsport Protein Particle complexes (TRAPPs) are ubiquitous regulators of membrane traffic mediating nucleotide exchange on the Golgi regulatory GTPases RAB1 and RAB11. In S. cerevisiae and metazoans TRAPPs consist of two large oligomeric complexes: RAB11-activating TRAPPII and RAB1-activating TRAP...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Pinar, Mario, Arias-Palomo, Ernesto, de los Ríos, Vivian, Arst, Herbert N., Peñalva, Miguel A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6946167/
https://ncbi.nlm.nih.gov/pubmed/31869332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008557
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