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The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits
BACKGROUND: Cola nitida is commonly chewed in many West African cultures to ease hunger pangs and sometimes for their stimulant and euphoriant qualities. Metoclopramide is a known substrate for P-gp, SULT2A1 and CYP2D6 and studies have revealed that caffeine- a major component of Cola nitida can ind...
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| 發表在: | BMC Pharmacol Toxicol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6945619/ https://ncbi.nlm.nih.gov/pubmed/31907041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-019-0379-6 |
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