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A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations

Pentameric ligand-gated ion channels are key players in mediating fast neurotransmission. Glycine receptors are chloride-selective members of this receptor family that mediate inhibitory synaptic transmission and are implicated in neurological disorders including autism and hyperekplexia. They have...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Dämgen, Marc A., Biggin, Philip C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945115/
https://ncbi.nlm.nih.gov/pubmed/31753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.10.019
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