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miR-107 modulates chondrocyte proliferation, apoptosis, and extracellular matrix synthesis by targeting PTEN

Background: Osteoarthritis (OA) is a common chronic degenerative disease, and the chondrocyte is reported to be a key player in OA progression. Increasing evidence has verified the regulatory role of miRNAs in OA. However, the function and underlying mechanism of miR-107 in cartilage function are st...

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Pubblicato in:Int J Clin Exp Pathol
Autori principali: Tian, Feng, Wang, Junhu, Zhang, Zhanhua, Yang, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6945102/
https://ncbi.nlm.nih.gov/pubmed/31933853
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