The spatial binding model of the pioneer factor Oct4 with its target genes during cell reprogramming

Understanding the target regulation between pioneer factor and its binding genes is crucial for improving the efficiency of TF-mediated reprogramming. Oct4 as the only one factor that cannot be substituted by other POU members, it is urgent need to develop a quantitative model for describing the spa...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Li, Hanshuang, Ta, Na, Long, Chunshen, Zhang, Qiutang, Li, Siyu, liu, Shuai, Yang, Lei, Zuo, Yongchun
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944736/
https://ncbi.nlm.nih.gov/pubmed/31921389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.09.002
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