Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy

Receptor tyrosine kinases (RTKs), such as HER2 and/or EGFR are important therapeutic targets in multiple cancer cells. Low and/or short response to targeted therapies are often due to activation of compensatory signaling pathways, and therefore a combination of kinase inhibitors with other anti-canc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Søgaard, Caroline K., Nepal, Anala, Petrovic, Voin, Sharma, Animesh, Liabakk, Nina-Beate, Steigedal, Tonje S., Otterlei, Marit
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944453/
https://ncbi.nlm.nih.gov/pubmed/31921382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27267
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