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Gabexate mesilate ameliorates the neuropathic pain in a rat model by inhibition of proinflammatory cytokines and nitric oxide pathway via suppression of nuclear factor-κB

BACKGROUND: This study examined the effects of gabexate mesilate on spinal nerve ligation (SNL)-induced neuropathic pain. To confirm the involvement of gabexate mesilate on neuroinflammation, we focused on the activation of nuclear factor-κB (NF-κB) and consequent the expression of proinflammatory c...

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Bibliografiske detaljer
Udgivet i:Korean J Pain
Main Authors: Oh, Seon Hee, Lee, Hyun Young, Ki, Young Joon, Kim, Sang Hun, Lim, Kyung Joon, Jung, Ki Tae
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Pain Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944363/
https://ncbi.nlm.nih.gov/pubmed/31888315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3344/kjp.2020.33.1.30
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