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Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway

Understanding the biosynthesis of cofactors is fundamental to the life sciences, yet to date a few important pathways remain unresolved. One example is the redox cofactor pyrroloquinoline quinone (PQQ) which is critical for C1 metabolism in many microorganisms, a disproportionate number of which are...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Koehn, Eric M., Latham, John A., Armand, Tara, Evans, Robert L., Tu, Xiongying, Wilmot, Carrie M., Iavarone, Anthony T., Klinman, Judith P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6944208/
https://ncbi.nlm.nih.gov/pubmed/30811189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13453
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