Melding Pharmacogenomic Effect of MDR1 and CYP3A5 Gene Polymorphism on Tacrolimus Dosing in Renal Transplant Recipients in Northern India

INTRODUCTION: Tacrolimus (TAC) is the mainstay immunosuppressant for renal transplantation. A narrow therapeutic index, multiple drug interactions, and interindividual variability in pharmacokinetics make it obligatory to monitor therapeutic drug levels. The Multidrug resistance gene 1 (MDR1) and CY...

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Detalhes bibliográficos
Publicado no:Kidney Int Rep
Main Authors: Prasad, Narayan, Jaiswal, Akhilesh, Behera, Manas Ranjan, Agarwal, Vikas, Kushwaha, Ravi, Bhadauria, Dharmendra, Kaul, Anupama, Gupta, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943758/
https://ncbi.nlm.nih.gov/pubmed/31922058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2019.09.013
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