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PEGylated Purpurin 18 with Improved Solubility: Potent Compounds for Photodynamic Therapy of Cancer

Purpurin 18 derivatives with a polyethylene glycol (PEG) linker were synthesized as novel photosensitizers (PSs) with the goal of using them in photodynamic therapy (PDT) for cancer. These compounds, derived from a second-generation PS, exhibit absorption at long wavelengths; considerable singlet ox...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Pavlíčková, Vladimíra, Rimpelová, Silvie, Jurášek, Michal, Záruba, Kamil, Fähnrich, Jan, Křížová, Ivana, Bejček, Jiří, Rottnerová, Zdeňka, Spiwok, Vojtěch, Drašar, Pavel, Ruml, Tomáš
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943672/
https://ncbi.nlm.nih.gov/pubmed/31817655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244477
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