Simultaneous Determination of Etomidate and Its Major Metabolite, Etomidate Acid, in Urine Using Dilute and Shoot Liquid Chromatography–Tandem Mass Spectrometry

Etomidate (ET) is a commonly used sedative-hypnotic agent such as propofol to induce anesthesia, and it is rapidly metabolized to etomidate acid (ETA) in liver. Herein, a simple method to determine ET and ETA in urine simultaneously was developed using liquid chromatography–tandem mass spectrometry...

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Pubblicato in:Molecules
Autori principali: Jung, Yu-Kyung, You, Soo Young, Kim, Seon-Yeong, Kim, Jin Young, Paeng, Ki-Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943581/
https://ncbi.nlm.nih.gov/pubmed/31817432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24244459
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