Increased HLA-DR expression and cortical demyelination in MS links with HLA-DR15

OBJECTIVE: To investigate molecular changes in multiple sclerosis (MS) normal-appearing cortical gray matter (NAGM). METHODS: We performed a whole-genome gene expression microarray analysis of human brain autopsy tissues from 64 MS NAGM samples and 42 control gray matter samples. We further examined...

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Pubblicato in:Neurol Neuroimmunol Neuroinflamm
Autori principali: Enz, Lukas Simon, Zeis, Thomas, Schmid, Daniela, Geier, Florian, van der Meer, Franziska, Steiner, Guido, Certa, Ulrich, Binder, Thomas Martin Christian, Stadelmann, Christine, Martin, Roland, Schaeren-Wiemers, Nicole
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943368/
https://ncbi.nlm.nih.gov/pubmed/31882398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000656
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