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Exploring trophoblast-specific Tead4 enhancers through chromatin conformation capture assays followed by functional screening

Tead4 is critical for blastocyst development and trophoblast differentiation. We assayed long-range chromosomal interactions on the Tead4 promoter in mouse embryonic stem (ES) cells and trophoblast stem (TS) cells. Using luciferase reporter assays with ES and TS cells for 34 candidate enhancer regio...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tomikawa, Junko, Takada, Shuji, Okamura, Kohji, Terao, Miho, Ogata-Kawata, Hiroko, Akutsu, Hidenori, Tanaka, Satoshi, Hata, Kenichiro, Nakabayashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943130/
https://ncbi.nlm.nih.gov/pubmed/31777916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1034
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