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CRISPR技术发展及其在骨和软骨组织工程中的应用
The CRISPR/Cas9 system, consisting of Cas9 nuclease and single guide RNA (sgRNA), is an emerging gene editing technology that can perform gene reprogramming operations such as deletion, insertion, and point mutation on DNA sequences targeted by sgRNA. In addition, CRISPR/dCas9 (a mutant that loses C...
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| 發表在: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
南方医科大学学报编辑部
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942994/ https://ncbi.nlm.nih.gov/pubmed/31907146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2019.12.19 |
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