Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases

Using midbrain cultures, we previously demonstrated that the noble gas xenon is robustly protective for dopamine (DA) neurons exposed to l-trans-pyrrolidine-2,4-dicarboxylate (PDC), an inhibitor of glutamate uptake used to generate sustained, low-level excitotoxic insults. DA cell rescue was observe...

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Bibliographic Details
Published in:J Neural Transm (Vienna)
Main Authors: Le Nogue, Déborah, Lavaur, Jérémie, Milet, Aude, Ramirez-Gil, Juan Fernando, Katz, Ira, Lemaire, Marc, Farjot, Géraldine, Hirsch, Etienne C., Michel, Patrick Pierre
Format: Artigo
Language:Inglês
Published: Springer Vienna 2019
Subjects:
Neurology and Preclinical Neurological Studies - Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942589/
https://ncbi.nlm.nih.gov/pubmed/31807953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-019-02112-x
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