Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy

According to cancer genome sequences, more than 90% of cases of pancreatic ductal adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables accurate detection and quantification of rare mutations. We assessed the dynamics of circulating tumor DNA (ct‐DNA) in patients with advanc...

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Vydáno v:Cancer Sci
Hlavní autoři: Sugimori, Makoto, Sugimori, Kazuya, Tsuchiya, Hiromi, Suzuki, Yoshimasa, Tsuyuki, Sho, Kaneta, Yoshihiro, Hirotani, Akane, Sanga, Katsuyuki, Tozuka, Yuichiro, Komiyama, Satoshi, Sato, Takeshi, Tezuka, Shun, Goda, Yoshihiro, Irie, Kuniyasu, Miwa, Haruo, Miura, Yuuki, Ishii, Tomohiro, Kaneko, Takashi, Nagahama, Masatsugu, Shibata, Wataru, Nozaki, Akito, Maeda, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942439/
https://ncbi.nlm.nih.gov/pubmed/31746520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14245
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