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The emerging role of SPOP protein in tumorigenesis and cancer therapy
The nuclear speckle-type pox virus and zinc finger (POZ) protein (SPOP), a representative substrate-recognition subunit of the cullin-RING E3 ligase, has been characterized to play a dual role in tumorigenesis and cancer progression. Numerous studies have determined that SPOP suppresses tumorigenesi...
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| Опубликовано в: : | Mol Cancer |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6942384/ https://ncbi.nlm.nih.gov/pubmed/31901237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1124-x |
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