Ultrafast two-photon imaging of a high-gain voltage indicator in awake behaving mice

Optical interrogation of voltage in deep brain locations with cellular resolution would be immensely useful for understanding how neuronal circuits process information. Here, we report ASAP3, a genetically encoded voltage indicator with 51% fluorescence modulation by physiological voltages, sub-mill...

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Veröffentlicht in:Cell
Hauptverfasser: Villette, Vincent, Chavarha, Mariya, Dimov, Ivan K., Bradley, Jonathan, Pradhan, Lagnajeet, Mathieu, Benjamin, Evans, Stephen W., Chamberland, Simon, Shi, Dongqing, Yang, Renzhi, Kim, Benjamin B., Ayon, Annick, Jalil, Abdelali, St-Pierre, Francois, Schnitzer, Mark J., Bi, Guoqiang, Toth, Katalin, Ding, Jun, Dieudonné, Stéphane, Lin, Michael Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941988/
https://ncbi.nlm.nih.gov/pubmed/31835034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.11.004
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