Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling

NAD[P]H:quinone oxidoreductase 1 (NQO1) regulates cell fate decisions in response to stress. Oxidative stress supports cancer maintenance and progression. Previously we showed that knockdown of NQO1 (NQO1(low)) prostate cancer cells upregulate pro-inflammatory cytokines and survival under hormone-de...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Thapa, Dinesh, Huang, Shih-Bo, Muñoz, Amanda R., Yang, Xiaoyu, Bedolla, Roble G., Hung, Chia-Nung, Chen, Chun-Liang, Huang, Tim H.-M., Liss, Michael A., Reddick, Robert L., Miyamoto, Hiroshi, Kumar, Addanki P., Ghosh, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941961/
https://ncbi.nlm.nih.gov/pubmed/31909204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0720-z
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