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Conditional control of RNA-guided nucleic acid cleavage and gene editing

Prokaryotes use repetitive genomic elements termed CRISPR (clustered regularly interspaced short palindromic repeats) to destroy invading genetic molecules. Although CRISPR systems have been widely used in DNA and RNA technology, certain adverse effects do occur. For example, constitutively active C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Wang, Shao-Ru, Wu, Ling-Yu, Huang, Hai-Yan, Xiong, Wei, Liu, Jian, Wei, Lai, Yin, Ping, Tian, Tian, Zhou, Xiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941951/
https://ncbi.nlm.nih.gov/pubmed/31900392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13765-3
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