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Wnt and Hedgehog: Secretion of Lipid-Modified Morphogens

Morphogens are signaling molecules produced by a localized source, specifying cell fate in a graded manner. The source secretes morphogens into the extracellular milieu to activate various target genes in an autocrine or paracrine manner. Here we describe various secreted forms of two canonical morp...

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Publicat a:Trends Cell Biol
Autors principals: Parchure, Anup, Vyas, Neha, Mayor, Satyajit
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941938/
https://ncbi.nlm.nih.gov/pubmed/29132729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2017.10.003
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