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GluA1 in central amygdala promotes opioid use and reverses inhibitory effect of pain

Increasing evidence suggests that long-term opioids and pain induce similar adaptive changes in the brain’s reward circuits, however, how pain alters the addictive properties of opioids remains poorly understood. In this study using a rat model of morphine self-administration (MSA), we found that sh...

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Vydáno v:Neuroscience
Hlavní autoři: Hou, Yuan-Yuan, Cai, You-Qing, Pan, Zhizhong Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941469/
https://ncbi.nlm.nih.gov/pubmed/31863796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.11.032
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