Anti-Vascular Endothelial Growth Factor Antibody Monotherapy Causes Destructive Advanced Periodontitis in Rice Rats (Oryzomys palustris)

OBJECTIVE: Angiogenesis inhibitors (AgI) are commonly used in combination chemotherapy protocols to treat cancer, and have been linked to osteonecrosis of the jaw (ONJ). However, it is unknown if AgI therapy alone is sufficient to induce ONJ. We have previously established an ONJ model in rice rats...

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Publicado no:Bone
Main Authors: Messer, J.G., Castillo, E.J., Abraham, A.M., Jiron, J.M., Israel, R., Yarrow, J.F., Thomas, S., Reynolds, M.C., Wnek, R.D., Jorgensen, M., Wanionok, N., Van Poznak, C., Bhattacharyya, I., Kimmel, D.B., Aguirre, J.I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941430/
https://ncbi.nlm.nih.gov/pubmed/31707108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.115141
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