BPEI-Induced Delocalization of PBP4 Potentiates β‑Lactams against MRSA

With its high morbidity rate and increasing resistance to treatment, methicillin-resistant Staphylococcus aureus (MRSA) is a grave concern in the medical field. In methicillin-susceptible strains, β-lactam antibiotics disable the penicillin binding proteins (PBPs) that cross-link the bacterial cell...

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Publicat a:Biochemistry
Autors principals: Hill, Melissa A., Lam, Anh K., Reed, Patricia, Harney, Madeline C., Wilson, Beatrice A., Moen, Erika L., Wright, Summer N., Pinho, Mariana G., Rice, Charles V.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941424/
https://ncbi.nlm.nih.gov/pubmed/31429286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00523
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