TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

BACKGROUND: The occurrence of a mediastinal germ cell tumor (GCT) and hematological malignancy in the same patient is very rare. Due to its rarity, there have been only two reports of the concurrent cases undergoing detailed genetic analysis with whole-exome sequencing (WES), and the possible clonal...

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Pubblicato in:BMC Cancer
Autori principali: Akizuki, Keiichi, Sekine, Masaaki, Kogure, Yasunori, Kameda, Takuro, Shide, Kotaro, Koya, Junji, Kamiunten, Ayako, Kubuki, Yoko, Tahira, Yuki, Hidaka, Tomonori, Kiwaki, Takumi, Tanaka, Hiroyuki, Sato, Yuichiro, Kataoka, Hiroaki, Kataoka, Keisuke, Shimoda, Kazuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941398/
https://ncbi.nlm.nih.gov/pubmed/31898539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6497-0
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