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Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas
BACKGROUND: Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four grades, each with distinct biology and outcome. Previous studies have focused on cell-line-based models and patient-derived xenogr...
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| Publicado no: | Cancer Cell Int |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941273/ https://ncbi.nlm.nih.gov/pubmed/31908598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1086-5 |
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