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Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells

BACKGROUND: Human placenta-derived mesenchymal stem cells (PD-MSCs) are powerful sources for cell therapy in regenerative medicine. However, a limited lifespan by senescence through mechanisms that are well unknown is the greatest obstacle. In the present study, we first demonstrated the characteriz...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Seok, Jin, Jung, Hyun Sook, Park, Sohae, Lee, Jung Ok, Kim, Chong Jai, Kim, Gi Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941254/
https://ncbi.nlm.nih.gov/pubmed/31900237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1471-y
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