Effects of Vedolizumab in Patients With Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases

BACKGROUND & AIMS: Gut-homing lymphocytes that express the integrin α4β7 and CCR9 might contribute to development of primary sclerosing cholangitis (PSC). Vedolizumab, which blocks the integrin α4β7, is used to treat patients with inflammatory bowel diseases (IBD), but there are few data on its...

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Publicado no:Clin Gastroenterol Hepatol
Main Authors: Lynch, Kate D., Chapman, Roger W., Keshav, Satish, Montano-Loza, Aldo J., Mason, Andrew L., Kremer, Andreas E., Vetter, Marcel, de Krijger, Manon, Ponsioen, Cyriel Y., Trivedi, Palak, Hirschfield, Gideon, Schramm, Christoph, Liu, Chung Heng, Bowlus, Christopher L., Estes, Derek J., Pratt, Daniel, Hedin, Charlotte, Bergquist, Annika, de Vries, Annemarie C., van der Woude, C. Janneke, Yu, Lei, Assis, David N., Boyer, James, Ytting, Henriette, Hallibasic, Emina, Trauner, Michael, Marschall, Hanns-Ulrich, Daretti, Luigi M., Marzioni, Marco, Yimam, Kidist K., Perin, Nicola, Floreani, Annarosa, Beretta-Piccoli, Benedetta Terziroli, Rogers, Jennifer K., Levy, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders for the American Gastroenterological Association 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941216/
https://ncbi.nlm.nih.gov/pubmed/31100458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2019.05.013
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