More Than One HMG-CoA Lyase: The Classical Mitochondrial Enzyme Plus the Peroxisomal and the Cytosolic Ones

There are three human enzymes with HMG-CoA lyase activity that are able to synthesize ketone bodies in different subcellular compartments. The mitochondrial HMG-CoA lyase was the first to be described, and catalyzes the cleavage of 3-hydroxy-3-methylglutaryl CoA to acetoacetate and acetyl-CoA, the c...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Arnedo, María, Latorre-Pellicer, Ana, Lucia-Campos, Cristina, Gil-Salvador, Marta, Antoñanzas-Peréz, Rebeca, Gómez-Puertas, Paulino, Bueno-Lozano, Gloria, Puisac, Beatriz, Pié, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941031/
https://ncbi.nlm.nih.gov/pubmed/31817290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246124
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