A Novel Hepatic Anti-Fibrotic Strategy Utilizing the Secretome Released from Etanercept-Synthesizing Adipose-Derived Stem Cells

Tumor necrosis factor-α (TNF-α)-driven inflammatory reaction plays a crucial role in the initiation of liver fibrosis. We herein attempted to design genetically engineered adipose-derived stem cells (ASCs) producing etanercept (a potent TNF-α inhibitor), and to determine the anti-fibrotic potential...

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Publicat a:Int J Mol Sci
Autors principals: Han, Jae Hyun, Kim, Ok-Hee, Lee, Sang Chul, Kim, Kee-Hwan, Park, Jung Hyun, Lee, Jae Im, Lee, Kyung Hee, Hong, Ha-Eun, Seo, Haeyeon, Choi, Ho Joong, Ju, Ji Hyeon, Kim, Say-June
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940971/
https://ncbi.nlm.nih.gov/pubmed/31847135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246302
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