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Development of Thiazolidinedione-Based HDAC6 Inhibitors to Overcome Methamphetamine Addiction
Thiazolidinedione is a five-membered heterocycle that is widely used in drug discovery endeavors. In this study, we report the design, synthesis, and biological evaluation of a series of thiazolidinedione-based HDAC6 inhibitors. In particular, compound 6b exerts an excellent inhibitory activity agai...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6940941/ https://ncbi.nlm.nih.gov/pubmed/31835389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246213 |
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