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Sertoli cell ablation and replacement of the spermatogonial niche in mouse

Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects in Sertoli cells often lead to infertility, but replacement of defective cells has been limited by the inability to deplete the existing popul...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yokonishi, Tetsuhiro, McKey, Jennifer, Ide, Shintaro, Capel, Blanche
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940386/
https://ncbi.nlm.nih.gov/pubmed/31896751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13879-8
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