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Sertoli cell ablation and replacement of the spermatogonial niche in mouse

Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects in Sertoli cells often lead to infertility, but replacement of defective cells has been limited by the inability to deplete the existing popul...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Yokonishi, Tetsuhiro, McKey, Jennifer, Ide, Shintaro, Capel, Blanche
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940386/
https://ncbi.nlm.nih.gov/pubmed/31896751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13879-8
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