Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia

BACKGROUND: Celiac disease (CD) is a systemic immune-mediated disorder developing in HLA genetically predisposed individuals carrying HLA-DQ2 and/or HLA-DQ8 molecules. Recent evidences supported a predominant importance of HLA-DQB1 locus and, in particular, HLA-DQB1*02 alleles. This diagnosis is poo...

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Publicado en:PLoS One
Autores principales: Poddighe, Dimitri, Turganbekova, Aida, Baymukasheva, Dana, Saduakas, Zhazira, Zhanzakova, Zhuldyz, Abdrakhmanova, Saniya
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939901/
https://ncbi.nlm.nih.gov/pubmed/31895924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226546
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