Randomized, Double-Blind, Pharmacokinetic Equivalence Trial Comparing DRL-Rituximab With MabThera in Patients With Diffuse Large B-Cell Lymphoma

PURPOSE: We sought to compare the pharmacokinetics (PKs) of DRL-rituximab (DRL_RI; potential biosimilar) and innovator rituximab MabThera (Roche, Grenzach-Wyhlen, Germany; reference medicinal product [RMP]) in patients with diffuse large B-cell lymphoma (DLBCL). Efficacy, pharmacodynamics (PDs), saf...

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Detalhes bibliográficos
Publicado no:J Glob Oncol
Main Authors: Viswabandya, Auro, Shah, Sandip, Mukhopadhyay, Asis, Nagarkar, Rajnish Vasant, Batra, Sonica Sachdeva, Lopez-Lazaro, Luis, Kankanwadi, Suresh, Srivastava, Alok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939748/
https://ncbi.nlm.nih.gov/pubmed/31809224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JGO.19.00248
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